• biological impact of phthalates | request pdf

    Biological impact of phthalates | Request PDF

    Request PDF | Biological impact of phthalates | Esters of phthalic acid are chemical agents used to improve the plasticity of industrial polymers. Their ubiquitous use in multiple commercial

  • biological impact of phthalates

    Biological impact of phthalates

    overall potential effects on biological systems and allows for comparison between phthalates with respect to each individual biological end point. 2. Materials and methods 2.1. Cytotoxicity MVLN cells were propagated in DMEM/F-12 media containing 10% FBS at 37 C, 5% CO2. Cytotoxicities of phthalates were determined by exposing 8×104 MVLN cells

  • phthalates: the everywhere chemical

    Phthalates: The Everywhere Chemical

    your healthcare provider to use phthalate-free tubing and medical bags especially for procedures such as blood transfusions and dialysis. What negative health effects have phthalates been shown to have in laboratory animals? Very few studies have examined the health effects of phthalates on humans. In lab animals, phthalate exposure

  • phthalates in food and medical devices | request pdf

    Phthalates in food and medical devices | Request PDF

    Request PDF | Phthalates in food and medical devices | Phthalates are ubiquitous environmental chemicals with a broad range of potential adverse health effects. Exposure pathways include air

  • metabolism of phthalates in humans | request pdf

    Metabolism of phthalates in humans | Request PDF

    Request full-text PDF. Phthalates have short biological half-lives (<24h) To understand and to treat the adverse effects of phthalates on human health, it is essential to expand the

  • biological impact of phthalates - sciencedirect

    Biological impact of phthalates - ScienceDirect

    Highlights Investigated the biological impact of phthalates DEHP, DEP, DBP and BBP. Phthalates differing in physicochemical properties have similar endpoints. Phthalates simultaneously affect multiple cellular targets. Demonstrated the need for the simultaneous assessment of multiple endpoints.

  • appendix e1 modeling consumer exposure to phthalate esters


    work was performed at the request of the Chronic Hazard Advisory Panel (CHAP) on phthalates and phthalate substitutes. These comments are those of the CPSC staff, have not been reviewed or approved by, and may not necessarily

  • cumulative risk assessment of phthalates in edible vegetable

    Cumulative risk assessment of phthalates in edible vegetable

    Both phthalates were detected in four major edible vegetable oil sources. The phthalate with the highest detection rate was DBP (13.48%), followed by DEHP (7.78%). The results of the cumulative risk assessment showed that the hazard indices of these two phthalates in edible vegetable oils were less than 1, except in soybean oil.

  • urinary phthalates and increased insulin resistance

    Urinary Phthalates and Increased Insulin Resistance

    Early life exposure to phthalates has been associated with a variety of adverse effects, particularly involving endocrine processes. 1, 8 Although an exploratory, cross-sectional analysis of the 1999–2002 US NHANES did not identify significant associations of urinary phthalate metabolites with BMI among children, 9 other analyses, including an analysis of 2003–2008 NHANES data, have found

  • antiandrogenic effects of dibutyl phthalate and its

    Antiandrogenic effects of dibutyl phthalate and its

    ABSTRACT Developmental toxicity following administration of dibutyl phthalate (DBF) and its major metabolite, monobutyl phthalate (MBuP), by gavage was determined in Wistar rats. DBF on days 0–8 of pregnancy induced an increase in the incidence of preimplantation loss at 1250 mg/kg and higher and postimplantation loss at 750 mg/kg and higher.

  • phthalates and other additives in plastics: human exposure

    Phthalates and other additives in plastics: human exposure

    Concern exists over whether additives in plastics to which most people are exposed, such as phthalates, bisphenol A or polybrominated diphenyl ethers, may cause harm to human health by altering endocrine function or through other biological mechanisms.

  • a critical analysis of the biological impacts of plasticizers

    A critical analysis of the biological impacts of plasticizers

    Topics: bisphenol A, endocrine disruption, diethylhexyl phthalate, butyl benzyl phthalate, dimethyl phthalate, dibutyl phthalate

  • human body burdens of chemicals used in plastic manufacture

    Human body burdens of chemicals used in plastic manufacture

    2005 Biological monitoring of the five major metabolites of di-(2-ethylhexyl)phthalate (DEHP) in human urine using column-switching liquid chromatography-tandem mass spectrometry. J. Chromatogr.