• di(2-ethylhexyl) phthalate-induced toxicity and peroxisome

    Di(2-ethylhexyl) phthalate-induced toxicity and peroxisome

    The plasticizer di(2-ethylhexyl) phthalate (DEHP) has been widely used in the manufacture of polyvinyl chloride-containing products such as medical and consumer goods. Humans can easily be exposed to it because DEHP is ubiquitous in the environment. Recent research on the adverse effects of DEHP has focused on reproductive and developmental toxicity in rodents and/or humans. DEHP is a

  • di(2-ethylhexyl) phthalate-induced toxicity and peroxisome

    Di(2-ethylhexyl) phthalate-induced toxicity and peroxisome

    Recent research on the adverse effects of DEHP has focused on reproductive and developmental toxicity in rodents and/or humans. DEHP is a representative of the peroxisome proliferators. Therefore, peroxisome proliferator-activated receptor alpha (PPARα)-dependent pathways are the expected mode of action of several kinds of DEHP-induced toxicities.

  • di(2-ethylhexyl) phthalate-induced toxicity and peroxisome

    Di(2-ethylhexyl) phthalate-induced toxicity and peroxisome

    Di(2-ethylhexyl) phthalate-induced toxicity and peroxisome proliferator-activated receptor alpha: a review Environ Health Prev Med . 2019 Jul 6;24(1):47. doi: 10.1186/s12199-019-0802-z.

  • di(2-ethylhexyl) phthalate-induced toxicity and peroxisome

    Di(2-ethylhexyl) phthalate-induced toxicity and peroxisome

    Di(2-ethylhexyl) phthalate-induced toxicity and peroxisome proliferator-activated receptor alpha: a review Yuki Ito1*, Michihiro Kamijima1 and Tamie Nakajima2 Abstract The plasticizer di(2-ethylhexyl) phthalate (DEHP) has been widely used in the manufacture of polyvinyl chloride-containing products such as medical and consumer goods.

  • di(2-ethylhexyl) phthalate-induced toxicity and peroxisome

    Di(2-ethylhexyl) phthalate-induced toxicity and peroxisome

    Di(2-ethylhexyl) phthalate-induced toxicity and peroxisome proliferator-activated receptor alpha: a review Article (PDF Available) in Environmental Health and Preventive Medicine 24(1) · December

  • di(2‐ethylhexyl)phthalate induces hepatic tumorigenesis

    Di(2‐ethylhexyl)phthalate Induces Hepatic Tumorigenesis

    Yuki Ito, Michihiro Kamijima, Tamie Nakajima, Di(2-ethylhexyl) phthalate-induced toxicity and peroxisome proliferator-activated receptor alpha: a review, Environmental Health and Preventive Medicine, 10.1186/s12199-019-0802-z, 24, 1, (2019).

  • di-(2-ethylhexyl) phthalate induced developmental

    Di-(2-ethylhexyl) phthalate induced developmental

    1. Introduction. Di-2-ethylhexyl phthalate (DEHP) is commonly used as a plasticizer in many daily used products (Rowdhwal and Chen, 2018).Because of annual production of over 2 million tons, DEHP has become one of the most widespread environmental contaminants (Halden, 2010).

  • subchronic toxicity of di(2-ethylhexyl)phthalate in common

    Subchronic Toxicity of Di(2-ethylhexyl)phthalate in Common

    To evaluate the toxicological effect, di(2-ethylhexyl)phthalate (DEHP) was administered orally at 100, 500, and 2500 mg/kg to four male and four female marmosets in each group for 13 weeks. Its potentials of hepatic peroxisome proliferation, testicular atrophy, and pancreatic acinar cell hyperplasia were evaluated more closely.

  • mechanisms of toxicity of di(2-ethylhexyl) phthalate on the

    Mechanisms of toxicity of di(2-ethylhexyl) phthalate on the

    This project investigated the effects of di(2-ethylhexyl) phthalate (DEHP), the most commonly used phthalate, on the reproductive health of male zebrafish (Danio rerio). Males were treated with 0.5, 50 and 5000 mg DEHP kg −1 (body weight) for a period of 10 days via intraperitoneal injection.

  • [pdf] toxic effects of di-2-ethylhexyl phthalate: an overview

    [PDF] Toxic Effects of Di-2-ethylhexyl Phthalate: An Overview

    Di-2-ethylhexyl phthalate (DEHP) is extensively used as a plasticizer in many products, especially medical devices, furniture materials, cosmetics, and personal care products. DEHP is noncovalently bound to plastics, and therefore, it will leach out of these products after repeated use, heating, and/or cleaning of the products. Due to the overuse of DEHP in many products, it enters and

  • activation of trim17 by pparγ is involved in di(2-ethylhexyl

    Activation of Trim17 by PPARγ is involved in Di(2-ethylhexyl

    Di-(2-ethylhexyl) phthalate (DEHP) is widely used as a plasticizer in plastics. Its reproductive toxicity and teratogenic effects are well known. DEHP can cause liver damage and peroxisome proliferation, as well as carcinogenesis. Animal study has shown that DEHP causes neurodegeneration in rat brain.

  • (pdf) receptor and nonreceptor-mediated organ-specific

    (PDF) Receptor and nonreceptor-mediated organ-specific

    Receptor and nonreceptor-mediated organ-specific toxicity of di(2- ethylhexyl)phthalate (DEHP) in peroxisome proliferator-activated receptor??- null mice November 1997 Toxicologic Pathology 26(2